Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Formulation

Phosphate-buffered solution; no preservatives or carrier proteins.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.

Application

ELISA, WB, IHC, IP

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay.

The optimal working dilution should be determined for each specific assay condition.
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Application Notes

Clone 11A50-B10 is reactive to the C-terminus of beta amyloid and is specific for the isoform ending at the 40th amino acid.

Application References

(PubMed link indicates BioLegend citation)

1. Watts JC, et al. 2014. Proc. Natl. Sci. USA 28:10323. (IHC-P) PubMed
2. Diomede L, et al. 2014. Neurobiol. Dis. 62:521. (Dot Plot) PubMed
3. Watanabe H, et al. 2012. J Neurosci. 15:5085. (ELISA) PubMed
4. Portelius E, et al. 2006. J. Proteome Res. 4:1010. (IP)
5. Vingtdeux V, et al. 2011. FASEB J. 25:219. (ELISA) PubMed
6. Ohmi K, et al. 2011. PLoS One 11:e27461. (IHC-Other) PubMed

Product Citations

1. Watts J, et al. 2014. Proc Natl Acad Sci U S A. 111:10323-10328. PubMed
2. Wu Y, et al. 2019. Nat Commun. 10:58. PubMed

RRID

AB_2564974 (BioLegend Cat. No. 805404)