| 產品編號 | bs-0368G-AF488 |
| 英文名稱 | Goat Anti-Mouse IgM / AF488 antibody |
| 中文名稱 | Alexa Fluor 488標記的羊抗小鼠IgM |
| 別 名 | Goat Anti-Mouse IgM (Alexa Fluor? 488); Immunoglobulin M; |
 | Specific References (6) | bs-0368G-AF488 has been referenced in 6 publications. [IF=10.723] Jie Zhou. et al. Hyaluronic acid-based dual network hydrogel with sustained release of platelet-rich plasma as a diabetic wound dressing. CARBOHYD POLYM. 2023 Aug;314:120924 IF ; Rat. [IF=8.679] Zhiyong Shen. et al. GLUT5-KHK axis-mediated fructose metabolism drives proliferation and chemotherapy resistance of colorectal cancer. Cancer Lett. 2022 May;534:215617 IF ; Human. [IF=7.367] Yitian Du. et al. Engineered Microglia Potentiate the Action of Drugs against Glioma Through Extracellular Vesicles and Tunneling Nanotubes. 2021 Feb 28 IF ; Mouse. [IF=6.633] Li-Ming Yu. et al. Icariin attenuates excessive alcohol consumption-induced susceptibility to atrial fibrillation through SIRT3 signaling. BBA-MOL BASIS DIS. 2022 Oct;1868:166483 IF ; Mouse. [IF=3.923] Yu M et al. Amino acids stimulate glycyl-tRNA synthetase nuclear localization for mammalian target of rapamycin expression in bovine mammary epithelial cells.(2018)J. Cell. Physiol. IF ; Mouse. [IF=3.89] Zhang, Minghui, et al. "Annexin A2 Positively Regulates Milk Synthesis and Proliferation of Bovine Mammary Epithelial Cells through the mTOR Signaling Pathway." Journal of Cellular Physiology (2017). IF(ICC) ; Mouse. |
| 抗體來源 | Goat |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse |
| 產品應用 | IF=1:100-1000, Flow-Cyt=1:100-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Liquid |
| 濃 度 | 2.0 mg/ml |
| 免 疫 原 | Native Mouse IgM |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol. |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
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