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PE-CY5標(biāo)記的羊抗人IgM

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產(chǎn)品編號bs-0345G-PE-CY5
英文名稱Goat Anti-Human IgM / PE-Cy5 antibody
中文名稱PE-CY5標(biāo)記的羊抗人IgM
別    名Goat Anti-Human IgM (PE-Cy5); Immunoglobulin M;   
抗體來源Goat
克隆類型Polyclonal
交叉反應(yīng)Human
產(chǎn)品應(yīng)用IF=1:100-1000, Flow-Cyt=1:100-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    狀Liquid
濃    度2.0 mg/ml
免 疫 原Native Human IgM 
亞    型IgG
純化方法affinity purified by Protein G
緩 沖 液10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol.
保存條件Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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