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重組小鼠頂膜鈉依賴性膽鹽轉(zhuǎn)運體蛋白

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產(chǎn)品編號bs-41358P
英文名稱Recombinant mouse SLC10A2 protein, N-Sumo
中文名稱重組小鼠頂膜鈉依賴性膽鹽轉(zhuǎn)運體蛋白
別    名SLC10A2; Apical sodium dependent bile acid transporter; Apical sodium- dependent bile acid transporter; IBAT; ileal apical sodium-dependent bile acid transporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na+ bile acid cotransporter; Na+ dependent ileal bile acid transporter; NTCP2; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family); Solute carrier family 10 member 2; Recombinant mouse SLC10A2 protein, N-Sumo  
理論分子量17.6kDa
檢測分子量24 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Mouse
序    列306-348/348
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)E.coli
活性Not tested
標(biāo)簽N-Sumo
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 86% as determined by reducing SDS-PAGE.
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