| 產(chǎn)品編號(hào) | bs-43157P |
| 英文名稱 | Recombinant SARS-Cov-2 Spike RBD protein (BQ.1.1/Omicron), His (HEK293) |
| 中文名稱 | 重組SARS冠狀病毒2 Spike突變蛋白R(shí)BD(BQ.1.1/Omicron) |
| 別 名 | SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2 |
| 理論分子量 | 26.7kDa |
| 性 狀 | Lyophilized or Liquid |
| 物 種 | SARS-Cov-2 |
| 純 度 | >90% as determined by SDS-PAGE |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | HEK293 cell |
| 標(biāo)簽 | C-His |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein. SWISS: P0DTC2 Gene ID: 43740568 |
| 產(chǎn)品圖片 |  Measured by its binding ability in a functional ELISA. Immobilized human ACE2, His-Avi Tag (Cat: bs-46001P) at 2μg/mL (100 μL/Well) can bind SARS-CoV-2 Spike RBD (BQ.1.1/Omicron), His Tag (Cat: bs-43157P), the EC50 is 34ng/mL.  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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