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重組人腦源神經(jīng)營養(yǎng)因子蛋白

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產(chǎn)品編號bs-2291P
英文名稱Recombinant human BDNF protein, His
中文名稱重組人腦源神經(jīng)營養(yǎng)因子蛋白
別    名Abrineurin; BDNF; BDNF; BDNF_HUMAN; Brain Derived Neurotrophic Factor; Brain-derived neurotrophic factor; MGC34632; MGC34632; Neurotrophin; Recombinant human BDNF protein, His  
理論分子量13kDa
檢測分子量14 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列129-247/247
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
活性Not tested
標(biāo)簽His
緩 沖 液20 mM Tris-HCl (pH=8.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and to a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family.

SWISS:
P23560

Gene ID:
627

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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