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重組小鼠3-磷酸甘油醛脫氫酶蛋白

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產(chǎn)品編號(hào)bs-41373P
英文名稱Recombinant mouse GAPDH protein, His
中文名稱重組小鼠3-磷酸甘油醛脫氫酶蛋白
別    名Glyceraldehyde-3-phosphate dehydrogenase; Recombinant mouse GAPDH protein, His  
理論分子量35.8kDa
檢測(cè)分子量38 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Mouse
序    列1-333/333
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
活性Not tested
標(biāo)簽His
緩 沖 液20 mM Tris-HCl (pH=8.0) with 200 mM Arg
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

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The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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