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重組人原癌基因Bcl-6蛋白

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產(chǎn)品編號bs-41380P
英文名稱Recombinant human Bcl-6 protein, N-Sumo
中文名稱重組人原癌基因Bcl-6蛋白
別    名Bcl-6/5; Bcl-6+Bcl-5; B-cell lymphoma 6 protein isoform 1; zinc finger transcription factor BCL6S; B-cell lymphoma 6 protein transcript; BCL-5; BCL6; Bcl 6; protein LAZ-3; B-cell lymphoma 5 protein; zinc finger and BTB domain-containing protein 27; lymphoma-associated zinc finger gene on chromosome 3; zinc finger protein 51; cys-his2 zinc finger transcription factor; BCL5; BCL6A; LAZ3; ZBTB27; ZNF51; BCL6_HUMAN; Recombinant human Bcl-6 protein, N-Sumo  
理論分子量70kDa
檢測分子量70 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列183-706/706
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)E.coli
活性Not tested
標簽N-Sumo
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq].

SWISS:
P41182

Gene ID:
604

產(chǎn)品圖片
The purity of the protein is greater than 68% as determined by reducing SDS-PAGE.
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