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重組人絲氨酸蛋白激酶Sgk3蛋白

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產(chǎn)品編號(hào)bs-41362P
英文名稱Recombinant human SGK3 protein
中文名稱重組人絲氨酸蛋白激酶Sgk3蛋白
別    名CISK; Cytokine independent survival kinase; Serine/threonine protein kinase Sgk3; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid regulated kinase family member 3; Serum/glucocorticoid regulated kinase like; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK 2; SGK 3; SGK2; Sgk3; SGK3_HUMAN; SGKL.  
理論分子量44.8kDa
檢測(cè)分子量42 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
序    列160-496/496
純    度>90% by SDSD-PAGE
內(nèi)毒素Not analyzed
活性No tested
標(biāo)簽N-His Tag
緩 沖 液PBS pH7.5
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Serine/threonine-protein kinase Sgk3 (SGK3), also designated serum/glucocorticoid regulated kinase 3, belongs to the Ser/Thr protein kinase family of proteins. The serum- and glucocorticoid-regulated kinase proteins are closely related to the Akt protein family. SGK1, a homolog of SGK3, activates ion channels, in particular potassium (K+) channels. SGK2 and SGK3 have been found to also be involved in this activation process, making all three of these proteins important regulators for cell proliferation, epithelial transport and neuromuscular excitability. SGK3 acts as a mediator of IL-3 dependent survival signals in the cell. It localizes to the early endosome and in vesicle-like structures. SGK3 is a widely expressed protein, but it is primarily detected in kidney, liver, pancreas, brain and heart. Phosphorylation of SGK3 at residue Ser 486 leads to an increase in SGK3 activation.

SWISS:
Q96BR1

Gene ID:
100533105

產(chǎn)品圖片
The purity of the protein is greater than 24% as determined by reducing SDS-PAGE.
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