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重組小鼠白細胞介素10蛋白

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產(chǎn)品編號bs-43113P
英文名稱Recombinant mouse IL-10 protein, N-His Tag (HEK293)
中文名稱重組小鼠白細胞介素10蛋白
別    名Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN; Recombinant mouse IL-10 protein, N-His Tag (HEK293)  
理論分子量14kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Mouse
序    列27-134/134
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)HEK293 cell
活性Not tested
標簽N-His Tag
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]

SWISS:
P18893

Gene ID:
16153

產(chǎn)品圖片
The purity of the protein is greater than 80% as determined by reducing SDS-PAGE.
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