產(chǎn)品編號 | bs-42136P |
英文名稱 | Recombinant human PLCG1 protein, C-His |
中文名稱 | 重組人磷酯酶Cγ1蛋白 |
別 名 | PLCG1_HUMAN; PLC gamma 1; 1 phosphatidyl D myo inositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; phosphatidylinositol phospholipase C; phosphodiesterase gamma 1; phosphoinositidase C; phosphoinositide phospholipase C; Phosphoinositide phospholipase C-gamma-1; Phospholipase C 148; Phospholipase C 148; phospholipase C gamma 1 (formerly subtype 148); Phospholipase C gamma 1; Phospholipase C gamma 1; phospholipase C-148; Phospholipase C-gamma-1; Phospholipase C-II; PLC 1; PLC 148; PLC II; PLC-148; PLC-gamma-1; PLC-II; PLC1; PLC148; PLCG 1; PLCG-1; PLCgamma1; PLCII; triphosphoinositide phosphodiesterase. |
理論分子量 | 22.6kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5mg/ml |
物 種 | Human |
序 列 | 476-650/1290 |
純 度 | >90% as determined by SDS-PAGE |
表達系統(tǒng) | E.coli |
活性 | Not tested |
標(biāo)簽 | N-His |
緩 沖 液 | 20mM Tris (pH=8.0) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. SWISS: P19174 Gene ID: 5335 |
產(chǎn)品圖片 | |
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