產(chǎn)品編號 | bs-42149P |
英文名稱 | Recombinant mouse NPHS2 protein |
中文名稱 | 重組小鼠腎小球裂孔膜蛋白PDCN |
別 名 | nephrosis 2, idiopathic, steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN. |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
物 種 | Mouse |
序 列 | 126-310/385 |
純 度 | >90% as determined by SDS-PAGE |
表達(dá)系統(tǒng) | E.coli |
活性 | Not tested |
緩 沖 液 | 20mM Tris (pH=8.0) with 8M Urea |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. SWISS: Q91X05 Gene ID: 170484 |
產(chǎn)品圖片 | |
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