| 產(chǎn)品編號 | bs-42071P |
| 英文名稱 | Recombinant human CIDEB protein, C-His |
| 中文名稱 | 重組人細(xì)胞死亡激活劑CIDEB蛋白 |
| 別 名 | cell death activator CIDE-B; cell death-inducing DFFA-like effector B; Cide-b; CIDEB_HUMAN. |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Human |
| 序 列 | 39-179/219 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not tested |
| 表達(dá)系統(tǒng) | E.coli |
| 標(biāo)簽 | C-His |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 8M Urea & 0.8M L-Arginine |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow. SWISS: Q546V8 Gene ID: 27141 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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