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人過氧化物酶體增殖物激活受體γ輔激活子1α重組蛋白

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產(chǎn)品編號bs-42280P
英文名稱Recombinant human PPARGC1A, N-Trx-His
中文名稱人過氧化物酶體增殖物激活受體γ輔激活子1α重組蛋白
別    名LEM6; PGC-1 Alpha; PGC1 Alpha; Ligand effect modulator 6; Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; Peroxisome proliferative activated receptor, gamma, coactivator 1 ; Peroxisome proliferator activated receptor gamma coactivator 1 alpha; PGC 1 (alpha); PGC 1 alpha; PGC 1v; PGC1; PGC1(alpha); PGC1A; PGC1v; PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6; PPAR gamma coactivator 1 alpha; PPAR gamma coactivator 1; PPAR gamma coactivator variant form; PPARGC 1 alpha.  
理論分子量47.8kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
序    列11-280/798
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)E.coli
標簽N-Trx-His
緩 沖 液20mM Tris-Hcl (pH=8.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

SWISS:
Q9UBK2

Gene ID:
10891

PGC-1α是一個新發(fā)現(xiàn)的轉錄激活因子,起到高游離脂肪酸刺激胰島α細胞分泌的重要調控作用。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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