| 產(chǎn)品編號 | bs-43636P |
| 英文名稱 | Recombinant human Glypican 3 protein, C-His (HEK293) |
| 中文名稱 | 重組人磷脂�；嫉鞍拙厶�-3 |
| 別 名 | GPC3; glypican3; glypican-3; Intestinal protein OCI-5; GTR2-2; MXR7.Intestinal protein OCI-5; GPC3_HUMAN. |
| 理論分子量 | 62.2kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >0.5mg/ml |
| 物 種 | Human |
| 序 列 | 25-559/580 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達系統(tǒng) | HEK293 cell |
| 標簽 | C-His |
| 緩 沖 液 | PBS (pH=7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] SWISS: P51654 Gene ID: 2719 GPC-3磷脂�；嫉鞍拙厶�-3是一種硫酸類肝素蛋白多糖，GPC-3在不同的組織中具有不同的生物學功能，甚至起著完全不同的作用，可能與腫瘤組織類型、發(fā)病機制等密切相關．GPC3在絕大多數(shù)HCC(肝細胞癌)患者有表達。 |
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