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重組人E選擇素蛋白

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產(chǎn)品編號(hào)bs-43646P
英文名稱Recombinant human E-Selectin protein, C-His (HEK293)
中文名稱重組人E選擇素蛋白
理論分子量60.6kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
序    列22-556/610
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)HEK293 cell
標(biāo)簽C-His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]

SWISS:
P16581

Gene ID:
6401

E選擇素(CD62E)是活化的內(nèi)皮細(xì)胞表面表達(dá)的黏附分子,是白細(xì)胞與內(nèi)皮細(xì)胞形成接觸時(shí)的啟動(dòng)因子。E選擇素是表達(dá)在血管內(nèi)皮細(xì)胞表面的黏附分子。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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