| 產(chǎn)品編號 | bs-42347P |
| 英文名稱 | Recombinant mouse Wnt11 protein, N-Trx-His |
| 中文名稱 | 重組小鼠信號通路Wnt11蛋白 |
| 別 名 | HWNT11; Protein Wnt-11; Wingless-related MMTV integration site 11; Wingless-type MMTV integration site family, member 1; Wingless-type MMTV integration site family, member 11; Wingless-type MMTV integration site family, member 11B; wnt-11; wnt11b; WNT11_HUMAN; WNT11_MOUSE. |
| 理論分子量 | 30kDa |
| 性 狀 | Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Mouse |
| 序 列 | 253-354/354 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達系統(tǒng) | E.coli |
| 標(biāo)簽 | N-Trx-His |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0). |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene ”wingless” and to its vertebrate ortholog, Int-1, a mouse proto-oncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins which have features typical of secreted growth factors. Wnt-11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Human Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is ex-pressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. The gene which encodes Wnt-11 maps to human chromosome 11q13.5. SWISS: O96014 Gene ID: 7481 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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